ChloroquineV1, Main, Exploration, bibRecord, 002D94

Immunotoxins to human small-cell lung cancer

Identifieur interne : 002D94 ( Main/Exploration ); précédent : 002D93; suivant : 002D95

Immunotoxins to human small-cell lung cancer

Auteurs : Edward J. Wawrzynczak [Royaume-Uni] ; Elaine J. Derbyshire [Royaume-Uni]

Source :

Cell Biophysics [ 0163-4992 ] ; 1992-08-01.

RBID : ISTEX:094975AD985633993D3F005C39E51B82D52F79B8

English descriptors

KwdEn :
- Ricin, immunotoxin, monoclonal antibody, mucin, small cell lung cancer.
Teeft :
- Activity criteria, Assay, Biophysics, Cancer research, Cell biophysics, Cell intoxication, Cell lung cancer, Chain control, Chain immunotoxin, Chain immunotoxin recognising, Clonogenic, Clonogenic efficiency, Clonogenic fraction, Cytotoxic, Cytotoxic activity, Cytotoxic effects, Cytotoxic potency, Cytotoxic properties, Deglycosylated ricin, Derbyshire, High proportion, Immunotoxin, Indirect assay, Kinetics, Mabs, Monensin, Monoclonal antibodies, Monoclonal antibodies recognising, Neural cell adhesion molecule, Normal tissues, Other agents, Other types, Potent effects, Protein synthesis, Rapid kinetics, Ricin, Sclc, Sclc cell lines, Sclc mabs, Second workshop, Selective activity, Similar antigens, Slow kinetics, Small cell lung cancer antigens, Systemic therapy, Target antigen, Target cells, Tissue culture, Tumor cells, Wawrzynczak, Weak activity.

Abstract

Abstract: Ricin A chain ITs directed against a variety of the common cell-surface antigens associated with SCLC exerted selective toxic effects on SCLC cell lines. The potency of the cytotoxic effects matched or exceeded that previously reported for ricin A chain ITs directed against identical or similar antigens on other types of carcinoma, suggesting that SCLC may be uniquely sensitive to this type of IT.

Url:

https://api.istex.fr/ark:/67375/1BB-TX8P2ZVM-M/fulltext.pdf

DOI: 10.1007/BF02789474

Affiliations:

Royaume-Uni

Links toward previous steps (curation, corpus...)

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to stream Istex, to step Curation: 002821
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to stream Main, to step Curation: 002D94

Le document en format XML

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<author><name sortKey="Derbyshire, Elaine J" sort="Derbyshire, Elaine J" uniqKey="Derbyshire E" first="Elaine J." last="Derbyshire">Elaine J. Derbyshire</name>
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<term>Cell biophysics</term>
<term>Cell intoxication</term>
<term>Cell lung cancer</term>
<term>Chain control</term>
<term>Chain immunotoxin</term>
<term>Chain immunotoxin recognising</term>
<term>Clonogenic</term>
<term>Clonogenic efficiency</term>
<term>Clonogenic fraction</term>
<term>Cytotoxic</term>
<term>Cytotoxic activity</term>
<term>Cytotoxic effects</term>
<term>Cytotoxic potency</term>
<term>Cytotoxic properties</term>
<term>Deglycosylated ricin</term>
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<term>Immunotoxin</term>
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<term>Monoclonal antibodies recognising</term>
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<term>Potent effects</term>
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<term>Rapid kinetics</term>
<term>Ricin</term>
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<term>Slow kinetics</term>
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<front><div type="abstract" xml:lang="en">Abstract: Ricin A chain ITs directed against a variety of the common cell-surface antigens associated with SCLC exerted selective toxic effects on SCLC cell lines. The potency of the cytotoxic effects matched or exceeded that previously reported for ricin A chain ITs directed against identical or similar antigens on other types of carcinoma, suggesting that SCLC may be uniquely sensitive to this type of IT.</div>
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Immunotoxins to human small-cell lung cancer

Immunotoxins to human small-cell lung cancer

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri